Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Oct 9;2(7989):765-8.
doi: 10.1016/s0140-6736(76)90600-0.

HLA antigens and atopic features in steroid-responsive nephrotic syndrome of childhood

P D Thomson, C R Stokes, T M Barratt, M W Turner, J F Soothill

HLA antigens and atopic features in steroid-responsive nephrotic syndrome of childhood

P D Thomson et al. Lancet. .

Abstract

Atopic systems were more common in children with steroid-responsive nephrotic syndrome (S.R.N.S.) than in matched controls, and HLA-B12 was more common in children with S.R.N.S. than in adult controls. Atopic symptoms (particularly hayfever), positive prick tests with grass pollen antigens, and a higher mean serum concentration of IgE antibody to timothy grass pollen were more common in nephrotic children with HLA-B12 than in those without HLA-B12. There was also an increased frequency of the haplotype HLA-A1 and HLA-B8, mainly among the non-atopic patients.

PubMed Disclaimer

LinkOut - more resources