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. 1984 Aug 4;2(8397):271-3.
doi: 10.1016/s0140-6736(84)90311-8.

Mass screening for neuroblastoma in infants in Japan. Interim report of a mass screening study group

T Sawada, M Hirayama, T Nakata, T Takeda, N Takasugi, T Mori, K Maeda, R Koide, Y Hanawa, A Tsunoda, et al.

Mass screening for neuroblastoma in infants in Japan. Interim report of a mass screening study group

T Sawada et al. Lancet. .

Abstract

A mass screening system for the early detection by means of a vanillylmandelic acid test of neuroblastoma in 6-month-old infants in Japan has been developed in eight districts. 16 of the 281 939 infants screened by this test had neuroblastoma, equivalent to a very high incidence of 1 in 17 621. 15 of the 16 children with neuroblastoma are alive; the other child died 1 month after surgery. This mass screening system for neuroblastoma used in infancy can help to improve prognosis in infants with this malignant disorder.

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