Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Sep 1;2(8401):489-93.
doi: 10.1016/s0140-6736(84)92566-2.

Lymphoproliferative disorders in cardiac transplant recipients are multiclonal lymphomas

M L Cleary, J Sklar

Lymphoproliferative disorders in cardiac transplant recipients are multiclonal lymphomas

M L Cleary et al. Lancet. .

Abstract

Tissue specimens from 5 immunosuppressed cardiac transplant recipients with lymphoproliferative disorders were examined for rearrangements in immunoglobulin DNA. In each case DNA analysis of tissues obtained from several sites or at various times showed different clonal immunoglobulin gene rearrangements for each of the three immunoglobulin gene loci. These findings indicate that lymphoproliferative disorders in immunosuppressed cardiac transplant recipients represent multiclonal or oligoclonal B cell lymphomas.

PubMed Disclaimer

Publication types

LinkOut - more resources