Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Aug;310(5979):644-9.
doi: 10.1038/310644a0.

Comparative biochemical properties of normal and activated human ras p21 protein

J P McGrath, D J Capon, D V Goeddel, A D Levinson

Comparative biochemical properties of normal and activated human ras p21 protein

J P McGrath et al. Nature. 1984 Aug.

Abstract

Human Ha-ras1 cDNAs encoding normal and activated p21 polypeptides have been efficiently expressed in Escherichia coli and the biochemical activities associated with each polypeptide compared. In addition to the guanine nucleotide binding activity, normal p21 displays a GTPase activity which is selectively impaired by a mutation which activates its oncogenic potential.

PubMed Disclaimer

LinkOut - more resources