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. 1976 Oct 16;2(7990):832-3.
doi: 10.1016/s0140-6736(76)91213-7.

The neurology of vitamin B12 deficiency. Metabolic mechanisms

The neurology of vitamin B12 deficiency. Metabolic mechanisms

E H Reynolds. Lancet. .

Abstract

The widely held view that the neurological and haematological complications of vitamin-B12 deficiency have different metabolic mechanisms appears unsound. It is suggested that the metabolic mechanisms involved are similar and that the neurological manifestations are the result of a secondary disturbance in folate metabolism as has already been postulated for the megaloblastosis.

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