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. 1980 Jan;124(1):48-51.

Cytolytic T lymphocyte precursors reactive against mutant Kb alloantigens are as frequent as those reactive against a whole foreign haplotype

M B Widmer, H R MacDonald
  • PMID: 6153106

Cytolytic T lymphocyte precursors reactive against mutant Kb alloantigens are as frequent as those reactive against a whole foreign haplotype

M B Widmer et al. J Immunol. 1980 Jan.

Abstract

Minimal frequencies of CTL-P in C57BL/6 spleen responding to H-2 mutational or whole haplotype differences were estimated by using a limiting dilution MLC technique. The frequency of CTL-P reacting against cells from each of three different H-2Kb mutant strains, carrying H-2 haplotypes ba, bg2, or bh, was determined to be within the range of frequencies of CTL-P directed against cells from strains carrying the independently derived H-2d and H-2k haplotypes.

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