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. 1980 Jan;29(1):26-30.
doi: 10.4269/ajtmh.1980.29.26.

Entamoeba histolytica "toxin": fetuin neutralizable and lectin-like

C F Mattern, D B Keister, P C Natovitz

Entamoeba histolytica "toxin": fetuin neutralizable and lectin-like

C F Mattern et al. Am J Trop Med Hyg. 1980 Jan.

Abstract

Extracts of Entamoeba histolytica produce rounding and agglutination of mammalian cells in tissue culture. This effect is inhibited or reversed by serum, by the serum glycoprotein, fetuin, or by N-acetyl-D-galactosamine. Concanavalin A produces a similar cytotoxic effect that is blocked or reversed by alpha-methyl mannoside. These properties suggest that the amebal "toxin" has a lectin-like activity.

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