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Comparative Study
. 1980 Jun;26(7):907-9.

Liquid-chromatographic assay of urinary 5-hydroxy-3-indoleacetic acid, with electrochemical detection

Z K Shihabi, J Scaro
  • PMID: 6155229
Comparative Study

Liquid-chromatographic assay of urinary 5-hydroxy-3-indoleacetic acid, with electrochemical detection

Z K Shihabi et al. Clin Chem. 1980 Jun.

Abstract

After extraction with two organic solvent mixtures, urinary 5-hydroxy-3-indoleacetic acid can be assayed by "high-performance" liquid chromatography on a reversed-phase column, with electrochemical detection. Compared to the nitrosonaphthol method (J. Biol. Chem. 216: 499, 1955), this method is more specific for detection of patients with carcinoid tumors.

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