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. 1980;77(2):169-80.
doi: 10.1007/BF00329542.

Cytological sub-division of S-phase in the Syrian hamster (Mesocricetus auratus)

J R Savage, S P Bhunya

Cytological sub-division of S-phase in the Syrian hamster (Mesocricetus auratus)

J R Savage et al. Chromosoma. 1980.

Abstract

Using BrdU/Hoechst 33258/Giemsa methods for detecting replicating chromosome bands, a method is described by which the DNA synthesis phase may be sub-divided on the basis of distinctive patterns displayed by certain chromosomes.--Applied to asynchronous populations successively sampled through one cell cycle, cells in S can be "unscrambled" and replaced in their correct time sequence.--This helps to overcome the sampling-time variable inherent in such populations, and allows a clearer picture of the progression of events both qualitatively and quantitatively.

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References

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