[Synthesis of alpha-fetoprotein in rat liver after a single injection of the liver carcinogen 4-dimethylaminoazobenzene and its noncarcinogenic isomer 4-diethylaminoazobenzene]
[Article in
Russian]
- PMID: 6156725
Item in Clipboard
[Synthesis of alpha-fetoprotein in rat liver after a single injection of the liver carcinogen 4-dimethylaminoazobenzene and its noncarcinogenic isomer 4-diethylaminoazobenzene]
[Article in
Russian]
Biull Eksp Biol Med.
1980 Jun.
Abstract
Single injection of the hepatospecific carcinogen 4-dimethylaminobenzene and its noncarcinogenic isomer 4-dimethylaminoazobenzene induced the foci of oval and transitional cells in the rat liver. Part of the cells synthesized alpha-fetoprotein. It is suggested that induction of the foci of the above cells and alpha-fetoprotein synthesis are likely to be due to the toxic effect of the two carcinogenic agents.
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