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Comparative Study
. 1980 May 10;8(9):1893-912.
doi: 10.1093/nar/8.9.1893.

Codon frequencies in 119 individual genes confirm consistent choices of degenerate bases according to genome type

R Grantham, C Gautier, M Gouy
Free PMC article
Comparative Study

Codon frequencies in 119 individual genes confirm consistent choices of degenerate bases according to genome type

R Grantham et al. Nucleic Acids Res. .
Free PMC article

Abstract

The poor printing of our previous Figure 2 (1) is corrected. Codon usage in mRNA sequences just published is also given. A new correspondence analysis is done, based on simultaneous comparison in all mRNA of use of the 61 codons. This analysis reinforces our claim that most genes in a genome, or genome type, have the same coding strategy; that is, they show similar choices among synonymous codons, or among degenerate bases (2). Like analysis on frequency variation in the amino acids coded reveals an entirely different pattern.

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