doi: 10.1073/pnas.77.7.4003.
Molecular cloning of human interferon cDNA
- PMID: 6159625
- PMCID: PMC349756
- DOI: 10.1073/pnas.77.7.4003
Item in Clipboard
Molecular cloning of human interferon cDNA
Proc Natl Acad Sci U S A.
1980 Jul.
Abstract
A hybrid plasmid, TpIF319, has been shown to contain the sequence for human fibroblast interferon mRNA [Taniguchi, T., Sakai, M., Fujii-Kuriyama, Y., Muramatsu, M., Kobayashi, S. & Sudo, T. (1979) Proc. Jpn. Acad. 55, Ser. B, 464-469]. This conclusion was confirmed by a hybridization-translation assay, using rabbit globin mRNA and its cDNA-containing plasmid as a control. Plasmid TpIF319 was used as probe and another recombinant plasmid, TpIF319-13, whose cDNA insert consists of about 800 base pairs, was isolated. Nucleotide sequence analysis of the cDNA revealed that the DNA in fact codes for human fibroblast interferon.
Similar articles
-
The nucleotide sequence of human fibroblast interferon cDNA.Gene. 1980 Jun;10(1):11-5. doi: 10.1016/0378-1119(80)90138-9. Gene. 1980. PMID: 6157601
-
Two interferon mRNAs in human fibroblasts: in vitro translation and Escherichia coli cloning studies.Proc Natl Acad Sci U S A. 1980 Dec;77(12):7152-6. doi: 10.1073/pnas.77.12.7152. Proc Natl Acad Sci U S A. 1980. PMID: 6164058 Free PMC article.
-
Synthesis of human fibroblast interferon by E. coli.Nucleic Acids Res. 1980 Sep 25;8(18):4057-74. doi: 10.1093/nar/8.18.4057. Nucleic Acids Res. 1980. PMID: 6159584 Free PMC article.
-
Isolation and characterization of a human fibroblast interferon gene and its expression in Escherichia coli.Rev Infect Dis. 1981 Nov-Dec;3(6):1186-95. doi: 10.1093/clinids/3.6.1186. Rev Infect Dis. 1981. PMID: 6177026 Review.
-
Design and construction of expression plasmid vectors in Escherichia coli.Methods Enzymol. 1990;185:14-37. doi: 10.1016/0076-6879(90)85005-9. Methods Enzymol. 1990. PMID: 2199776 Review. No abstract available.
Cited by
-
Interferons: signaling, antiviral and viral evasion.Immunol Lett. 2009 Jan 29;122(1):1-11. doi: 10.1016/j.imlet.2008.11.002. Epub 2008 Dec 6. Immunol Lett. 2009. PMID: 19059436 Free PMC article. Review.
-
Interferon induction and function at the mucosal surface.Immunol Rev. 2013 Sep;255(1):25-39. doi: 10.1111/imr.12101. Immunol Rev. 2013. PMID: 23947345 Free PMC article. Review.
-
Epstein-Barr virus shuttle vector for stable episomal replication of cDNA expression libraries in human cells.Mol Cell Biol. 1988 Jul;8(7):2837-47. doi: 10.1128/mcb.8.7.2837-2847.1988. Mol Cell Biol. 1988. PMID: 2841588 Free PMC article.
-
Expression of the human fibroblast interferon gene in Escherichia coli.Proc Natl Acad Sci U S A. 1980 Sep;77(9):5230-3. doi: 10.1073/pnas.77.9.5230. Proc Natl Acad Sci U S A. 1980. PMID: 6159642 Free PMC article.
-
Inhibition of interferon secretion in human fibroblast by vinblastine.Arch Virol. 1982;73(3-4):343-9. doi: 10.1007/BF01318088. Arch Virol. 1982. PMID: 7149998
References
MeSH terms
Substances
Associated data
- Actions
- Actions
- Actions
LinkOut - more resources
Full Text Sources
Other Literature Sources
