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. 1981 Feb;78(2):1167-70.
doi: 10.1073/pnas.78.2.1167.

Two allelic forms of mouse beta 2-microglobulin

P J Robinson, L Graf, K Sege

Two allelic forms of mouse beta 2-microglobulin

P J Robinson et al. Proc Natl Acad Sci U S A. 1981 Feb.

Abstract

Two allelic forms of mouse beta 2-microglobulin (beta 2m), the small polypeptide chain of H-2 histocompatibility antigens, have been identified. The two forms can be distinguished by NaDodSO4/polyacrylamide gel electrophoresis. All inbred mouse strains express a single beta 2m isotype. Mice heterozygous for beta 2m synthesize both forms, showing codominant expression of beta 2m alleles. In mice heterozygous for both H-2 and beta 3m, individual H-2 histocompatibility antigens associate with both beta 2m forms. Preliminary structural studies indicate differences in peptide composition between the two forms.

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References

    1. Proc Natl Acad Sci U S A. 1973 Apr;70(4):1108-11 - PubMed
    1. Transplant Rev. 1974;21(0):15-34 - PubMed
    1. Transplant Rev. 1974;21(0):85-105 - PubMed
    1. Eur J Biochem. 1975 Aug 15;56(2):335-41 - PubMed
    1. J Cell Biol. 1975 Dec;67(3):835-51 - PubMed

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