doi: 10.1128/AAC.19.4.672.
Combined antiviral effect of interferon and acyclovir on herpes simplex virus types 1 and 2
- PMID: 6166248
- PMCID: PMC181499
- DOI: 10.1128/AAC.19.4.672
Item in Clipboard
Combined antiviral effect of interferon and acyclovir on herpes simplex virus types 1 and 2
Antimicrob Agents Chemother.
1981 Apr.
Abstract
Acyclovir and human interferon displayed an additive to synergistic effect in reducing the number of herpes simplex viral plaque-forming units in Vero cells, suggesting a therapeutic potential for such combination therapy.
Similar articles
-
Potent synergistic inhibition of herpes simplex virus-2 by 9-[(1, 3-dihydroxy-2-propoxy)methyl]guanine in combination with recombinant interferons.Biochem Biophys Res Commun. 1984 Apr 16;120(1):66-73. doi: 10.1016/0006-291x(84)91414-1. Biochem Biophys Res Commun. 1984. PMID: 6201172
-
Alpha interferon and acyclovir treatment of herpes simplex virus in lymphoid cell cultures.Antimicrob Agents Chemother. 1982 Apr;21(4):634-40. doi: 10.1128/AAC.21.4.634. Antimicrob Agents Chemother. 1982. PMID: 6177287 Free PMC article.
-
Effects of acyclovir, oxetanocin-G, and carbocyclic oxetanocin-G in combinations on the replications of herpes simplex virus type 1 and type 2 in Vero cells.Tohoku J Exp Med. 1992 May;167(1):57-68. doi: 10.1620/tjem.167.57. Tohoku J Exp Med. 1992. PMID: 1333651
-
Mechanism of action and selectivity of acyclovir.Am J Med. 1982 Jul 20;73(1A):7-13. doi: 10.1016/0002-9343(82)90055-9. Am J Med. 1982. PMID: 6285736 Review.
-
Drug therapy: antiviral agents (second of two parts).N Engl J Med. 1980 Apr 24;302(17):949-53. doi: 10.1056/NEJM198004243021705. N Engl J Med. 1980. PMID: 6244492 Review. No abstract available.
Cited by
-
Synergistic effect of human leukocyte interferon and nonoxynol 9 against herpes simplex virus type 2.Antimicrob Agents Chemother. 1985 Sep;28(3):449-51. doi: 10.1128/AAC.28.3.449. Antimicrob Agents Chemother. 1985. PMID: 3000288 Free PMC article.
-
Synergistic antiviral activity of acyclovir and interferon on human cytomegalovirus.Antimicrob Agents Chemother. 1983 Sep;24(3):325-32. doi: 10.1128/AAC.24.3.325. Antimicrob Agents Chemother. 1983. PMID: 6314891 Free PMC article.
-
Downregulation of cellular c-Jun N-terminal protein kinase and NF-κB activation by berberine may result in inhibition of herpes simplex virus replication.Antimicrob Agents Chemother. 2014 Sep;58(9):5068-78. doi: 10.1128/AAC.02427-14. Epub 2014 Jun 9. Antimicrob Agents Chemother. 2014. PMID: 24913175 Free PMC article.
-
Human gamma interferon and tumor necrosis factor exert a synergistic blockade on the replication of herpes simplex virus.J Virol. 1989 Mar;63(3):1354-9. doi: 10.1128/JVI.63.3.1354-1359.1989. J Virol. 1989. PMID: 2536838 Free PMC article.
-
Comparative activities of selected combinations of acyclovir, vidarabine, arabinosyl hypoxanthine, interferon, and polyriboinosinic acid-polyribocytidylic acid complex against herpes simplex virus type 2 in tissue culture and intravaginally inoculated mice.Antimicrob Agents Chemother. 1984 Oct;26(4):557-62. doi: 10.1128/AAC.26.4.557. Antimicrob Agents Chemother. 1984. PMID: 6083754 Free PMC article.
References
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
