Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1981 Mar;3(1):89-104.
doi: 10.1007/BF02782155.

A general interactive model for B cell activation II. Experimental verification

A J Rosenspire, D M Jacobs

A general interactive model for B cell activation II. Experimental verification

A J Rosenspire et al. Cell Biophys. 1981 Mar.

Abstract

The general interactive model described in the previous paper was subjected to experimental testing. We examined the high affinity anti-TNP plaque-forming cell response of cultures of murine lymphocytes exposed to lipopolysaccharide and trinitrophenylated lipopolysaccharide (TNP--LPS). From our model we predicted the effects of the addition of free LPS on the dose response to TNP--LPS, the effect of the addition of Polymyxin B to cultures stimulated with TNP--LPS, and the effect on the response to TNP--LPS preparations with different haptenation ratios. The results obtained were consistent with the predictions of the general interactive model.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. Transplant Rev. 1975;23:223-49 - PubMed
    1. Transplant Rev. 1975;23:37-48 - PubMed
    1. Transplant Rev. 1975;23:126-37 - PubMed
    1. J Immunol. 1975 Jan;114(1 Pt 2):360-4 - PubMed
    1. J Exp Med. 1975 Jun 1;141(6):1453-8 - PubMed

Publication types