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Comparative Study
. 1981;17(7):1294-8.

[Interferon as a protector in human cells treated with 4-nitroquinoline-1-oxide]

[Article in Russian]
T P Shvetsova, G D Zasukhina, T A Bektemirov, A V Andronova, E P Barkova
  • PMID: 6168515
Comparative Study

[Interferon as a protector in human cells treated with 4-nitroquinoline-1-oxide]

[Article in Russian]
T P Shvetsova et al. Genetika. 1981.

Abstract

Interferon having the activity 25-37 and 375 IU/ml decreases the frequency of chromosome aberrations induced with the cancerogen 4-nitroquinoline-1-oxide in diploid human cells. The protective effect of interferon is not connected with stimulation or inhibition of cell division. It has been revealed that interferon with the activity 25-37 IU/ml has a stimulating effect on mitotic activity of cells, while interferon with the activity 375 IU/ml inhibits cell division.

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