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. 1981 May;19(5):922-4.
doi: 10.1128/AAC.19.5.922.

Combined protective effects on interferon and interferon induction on herpes simplex and ectromelia virus infections in mice

J Imanishi, M Matsubara, C J Won, H Nomura, T Kishida

Combined protective effects on interferon and interferon induction on herpes simplex and ectromelia virus infections in mice

J Imanishi et al. Antimicrob Agents Chemother. 1981 May.

Abstract

Mouse interferon or the induction of mouse interferon with polyriboinosinic acid-polyribocytidylic acid significantly protected mice against herpes simplex and ectromelia viral infections. When polyriboinosinic acid-polyribocytidylic acid was administered 24 h before herpes simplex or ectromelia viral infection and mouse interferon was administered shortly before and 24 h after infection, a combined protective effect against either herpes simplex or ectromelia viral infection in mice was evident. There was a significant decrease in the mortality rate with the combined treatment as compared either with the rate in group treated with interferon or polyriboinosinic acid-polyribocytidylic acid.

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References

    1. Infect Immun. 1979 Sep;25(3):831-7 - PubMed
    1. Nature. 1965 Oct 30;208(5009):456-8 - PubMed
    1. J Infect Dis. 1974 Nov;130(5):549-52 - PubMed
    1. J Gen Virol. 1976 Apr;31(1):59-64 - PubMed
    1. Antimicrob Agents Chemother. 1979 Mar;15(3):420-7 - PubMed