Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1981;220(2):427-33.
doi: 10.1007/BF00210519.

Occurrence of uranaffin-positive synaptic vesicles in both adrenergic and non-adrenergic nerves of the rat anococcygeus muscle

Occurrence of uranaffin-positive synaptic vesicles in both adrenergic and non-adrenergic nerves of the rat anococcygeus muscle

T Iijima. Cell Tissue Res. 1981.

Abstract

The uranaffin reaction in rat anococcygeus muscle, which receives a dual innervation of both adrenergic and non-cholinergic, non-adrenergic nerves was examined. Dense reaction product was observed in the vesicular membranes and/or the cores of some synaptic vesicles in the adrenergic nerve terminals. Occasional vesicles were filled up with dense reaction product. In the prominent population of small clear vesicles, however, no dense reaction product was observed. The number of small granular vesicles in the adrenergic nerve terminals was markedly increased after the administration of 5-hydroxydopamine (5-OHDA). These granular vesicles were moderately stained with uranaffin deposit on the cores but their limiting membranes possessed no uranaffin deposit at all. In the non-adrenergic nerve terminals, on the other hand, uranaffin deposit of variable density was observed on the cores of large granular vesicles but never on their limiting membranes or on the small clear vesicles. There was no change in the axon profiles after the administration of 5-OHDA. The possible occurrence of purines in the cores of large granular vesicles in the non-adrenergic nerves is discussed.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Br J Pharmacol. 1974 Jan;50(1):109-18 - PubMed
    1. Neurosci Lett. 1979 Jun;13(1):19-23 - PubMed
    1. Cell Tissue Res. 1979 Aug;200(2):257-71 - PubMed
    1. Br J Pharmacol. 1979 Mar;65(3):377-88 - PubMed
    1. Cell Tissue Res. 1976 Sep 1;171(4):407-23 - PubMed