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. 1981 Oct;90(2):143-7.
doi: 10.1016/0165-1218(81)90077-x.

Effect of human leukocyte interferon on human lymphocytes in vitro: cytogenetic studies

J P Sørensen, M K Jensen, C Jersild

Effect of human leukocyte interferon on human lymphocytes in vitro: cytogenetic studies

J P Sørensen et al. Mutat Res. 1981 Oct.

Abstract

Mitogen-stimulated lymphocytes from 8 healthy donors were exposed to interferon, and cytogenetic studies were preformed. The response of lymphocytes to the mitogens phytohemagglutinin (PHA), concanavalin A (con A) and pokeweed mitogen (PWM) was inhibited by interferon, whereas an increased number of structural chromosomal aberrations was not detected. Further investigations of the cytogenetic effects of interferon are needed.

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