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. 1982 Jan 14;295(5845):116-9.
doi: 10.1038/295116a0.

Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells

A Eva, K C Robbins, P R Andersen, A Srinivasan, S R Tronick, E P Reddy, N W Ellmore, A T Galen, J A Lautenberger, T S Papas, E H Westin, F Wong-Staal, R C Gallo, S A Aaronson

Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells

A Eva et al. Nature. .

Abstract

Polyadenylated RNAs of certain human tumour cell lines are shown to contain transcripts related to the cell-derived transforming onc genes of molecularly cloned primate, murine or avian transforming retrovirus genomes. Thus, analogues of retroviral transforming genes are both present and frequently expressed in human neoplastic cells.

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