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. 1982 Apr 1;155(4):1198-203.
doi: 10.1084/jem.155.4.1198.

Cytotoxic T lymphocytes produce immune interferon in response to antigen or mitogen

J R Klein, D H Raulet, M S Pasternack, M J Bevan

Cytotoxic T lymphocytes produce immune interferon in response to antigen or mitogen

J R Klein et al. J Exp Med. .

Abstract

Interferon (IFN) was found to be secreted by cloned lines of murine cytotoxic T lymphocytes in response to mitogenic or antigen specific stimulation. The IFN produced was shown to be of the immune type based on its sensitivity to pH 2.0 and on the ability of an antiserum to immune IFN to neutralize the antiviral activity.

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References

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