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. 1981 Dec;19(11-12):1055-62.
doi: 10.1007/BF00484564.

Genetic analysis of human salivary alpha-amylase isozymes by isoelectric focusing

P D Eckersall, J A Beeley

Genetic analysis of human salivary alpha-amylase isozymes by isoelectric focusing

P D Eckersall et al. Biochem Genet. 1981 Dec.

Abstract

The isozymes of human salivary alpha-amylase have been separated by thin-layer gel isoelectric focusing in a pH 4-8 gradient followed by a starch-iodine zymogram procedure. The normal isozyme pattern (N) consisted of five major isozymes together with a number of minor ones. In addition, seven variant isozyme phenotypes were also observed, which had a combined frequency of 11.7% in a random population of 368 individuals. Analysis of familial data is indicative of the inheritance of autosomal codominant alleles.

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