doi: 10.1016/0167-4781(82)90062-8.
The fluidity of the nuclear envelope lipid does not affect the rate of nucleocytoplasmic RNA transport in mammalian liver
- PMID: 6175344
- DOI: 10.1016/0167-4781(82)90062-8
Item in Clipboard
The fluidity of the nuclear envelope lipid does not affect the rate of nucleocytoplasmic RNA transport in mammalian liver
Biochim Biophys Acta.
.
Abstract
The effects of in vitro and in vivo modifications of nuclear envelope lipid on DNa leakage and on ATP-stimulated RNA release from isolated rat liver nuclei were investigated. The modifications included corn-oil feeding of the animals to alter the fatty acid composition of the lipids, phospholipase treatment of the isolated nuclei, and extraction of the total lipid with Triton X-100. Significant changes in lipid composition and approximate order parameter values of the spin-label 5-doxylstearate resulted, but there was no significant effect on RNA transport rate. It was concluded that the nuclear envelope lipid does not play any important part in nucleocytoplasmic RNA transport in mammalian liver.
Similar articles
-
Nucleocytoplasmic RNA transport.Mol Cell Biochem. 1985 Jul;67(2):87-99. doi: 10.1007/BF02370167. Mol Cell Biochem. 1985. PMID: 2413344 Review.
-
Changes of nuclear membrane lipid composition affect RNA nucleocytoplasmic transport.Biochem Biophys Res Commun. 1999 May 10;258(2):476-81. doi: 10.1006/bbrc.1999.0659. Biochem Biophys Res Commun. 1999. PMID: 10329412
-
Ribonucleic acid efflux from isolated mouse liver nuclei is altered by diet and genotypically determined change in nuclear envelope composition.Biochim Biophys Acta. 1988 May 9;940(1):33-42. doi: 10.1016/0005-2736(88)90005-3. Biochim Biophys Acta. 1988. PMID: 2452656
-
Nuclear membrane lipid peroxidation products bind to nuclear macromolecules.Arch Biochem Biophys. 1989 Mar;269(2):548-54. doi: 10.1016/0003-9861(89)90139-2. Arch Biochem Biophys. 1989. PMID: 2493218
-
Mechanics of nuclear membranes.J Cell Sci. 2019 Jul 15;132(14):jcs229245. doi: 10.1242/jcs.229245. J Cell Sci. 2019. PMID: 31308244 Free PMC article. Review.
Cited by
-
An assessment of some methodological criticisms of studies of RNA efflux from isolated nuclei.Biochem J. 1983 Sep 15;214(3):915-21. doi: 10.1042/bj2140915. Biochem J. 1983. PMID: 6194787 Free PMC article.
-
Nucleocytoplasmic RNA transport.Mol Cell Biochem. 1985 Jul;67(2):87-99. doi: 10.1007/BF02370167. Mol Cell Biochem. 1985. PMID: 2413344 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
