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. 1982;170(3):155-72.
doi: 10.1007/BF02298196.

Activation and role of natural killer cells in virus infections

C A Biron, R M Welsh

Activation and role of natural killer cells in virus infections

C A Biron et al. Med Microbiol Immunol. 1982.

Abstract

Natural killer cells may play a significant role in virus infections. Virus-induced interferon activates these cells to become highly cytotoxic, and viral infections may also affect the proliferation of such cells. Non-immune mice have an apparently cellular defense mechanism which rapidly lyses implanted virus-infected cells. The evidence for NK cell involvement in viral disease is reviewed.

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