Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Mar;41(3):1112-7.
doi: 10.1128/JVI.41.3.1112-1117.1982.

MCF-specific murine monoclonal antibodies made against AKR-247 MCF virus recognize a unique determinant associated with the gp70-p-15(E) complex

MCF-specific murine monoclonal antibodies made against AKR-247 MCF virus recognize a unique determinant associated with the gp70-p-15(E) complex

M W Cloyd et al. J Virol. 1982 Mar.

Abstract

Hybridomas obtained from (NFS X AKR)F mice immunized with syngeneic cells infected with AKR-247 MCF virus produced antibodies specific for only AKR-247 or closely related MCF viruses which hare a previously defined MCF antigen (MCFA-3). These monoclonal antibodies recognized a new type of viral antigenic determinant which appeared to be a conformational determinant associated with the env precursor polyprotein (pr80env) or its disulfide-linked gp70-p15(E) complex (gp80) but not with free gp70 or p15(E) or any other virion or virus-induced protein.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Virology. 1970 Dec;42(4):1136-9 - PubMed
    1. J Antibiot (Tokyo). 1971 Apr;24(4):215-23 - PubMed
    1. Proc Natl Acad Sci U S A. 1972 Dec;69(12):3790-4 - PubMed
    1. Eur J Biochem. 1974 Jul 1;46(1):83-8 - PubMed
    1. Cold Spring Harb Symp Quant Biol. 1975;39 Pt 2:1085-101 - PubMed