doi: 10.1007/BF02123316.
Killer T cell responses to influenza A during a drift period: studies in mice
- PMID: 6178951
- DOI: 10.1007/BF02123316
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Killer T cell responses to influenza A during a drift period: studies in mice
Med Microbiol Immunol.
1982.
Abstract
After intravenous immunization of mice with any influenza A H3N2 drift strain attempts to restimulation of cytotoxic T cell (CTL) activities with the same virus or other drift period variants were unsuccessful for up to 6 weeks. Cross-stimulation 4-5 months after primary sensitization yielded, in most situations, positive but lower--as compared to primary--secondary cytotoxic T cell responses. Homotypic challenge was also effective after priming with some influenza A subtypes (A/E/72, A/PC/73, A/T/77) at this time.
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