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. 1982;170(4):255-64.
doi: 10.1007/BF02123316.

Killer T cell responses to influenza A during a drift period: studies in mice

D Armerding, H Rossiter, E Liehl

Killer T cell responses to influenza A during a drift period: studies in mice

D Armerding et al. Med Microbiol Immunol. 1982.

Abstract

After intravenous immunization of mice with any influenza A H3N2 drift strain attempts to restimulation of cytotoxic T cell (CTL) activities with the same virus or other drift period variants were unsuccessful for up to 6 weeks. Cross-stimulation 4-5 months after primary sensitization yielded, in most situations, positive but lower--as compared to primary--secondary cytotoxic T cell responses. Homotypic challenge was also effective after priming with some influenza A subtypes (A/E/72, A/PC/73, A/T/77) at this time.

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