doi: 10.1084/jem.156.3.744.
Multiple human beta interferon genes
- PMID: 6180119
- PMCID: PMC2186800
- DOI: 10.1084/jem.156.3.744
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Multiple human beta interferon genes
J Exp Med.
.
Abstract
Analysis of human beta interferon (IFN) mRNA preparations obtained from poly(I) . poly (C)-induced human diploid fibroblasts (FS-4) and from several similarly induced human-mouse somatic cell hybrids by electrophoresis through agarose-CH3HgOH tube gels led to the detection of at least five translationally active human IFN-beta mRNA species. The results obtained are consistent with the existence of IFN-beta genes on different human chromosomes. Marked cell-dependent variability in the expression of these IFN mRNA species was observed.
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