doi: 10.1007/BF00777238.
Mechanism of linear DNA circularization: formation of 'lasso'-like structures of pre-mRNA DNA copies
- PMID: 6181388
- DOI: 10.1007/BF00777238
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Mechanism of linear DNA circularization: formation of 'lasso'-like structures of pre-mRNA DNA copies
Mol Biol Rep.
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Abstract
An electron microscopic investigation of a DNA product synthesized on the pre-mRNA template using AMV reverse transcriptase in the absence of actinomycin D revealed linear single-stranded and double-stranded molecules, and, also, double-stranded branched as well as 'lasso'-like and circular structures. Models for the formation of such DNA structures are proposed.
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