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. 1982 Apr 16;8(3):129-32.
doi: 10.1007/BF00777238.

Mechanism of linear DNA circularization: formation of 'lasso'-like structures of pre-mRNA DNA copies

V M Kavsan, A V Rynditch, A D Shved

Mechanism of linear DNA circularization: formation of 'lasso'-like structures of pre-mRNA DNA copies

V M Kavsan et al. Mol Biol Rep. .

Abstract

An electron microscopic investigation of a DNA product synthesized on the pre-mRNA template using AMV reverse transcriptase in the absence of actinomycin D revealed linear single-stranded and double-stranded molecules, and, also, double-stranded branched as well as 'lasso'-like and circular structures. Models for the formation of such DNA structures are proposed.

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