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. 1982;28(4):225-32.

Isolated fractions of the growth-promoting alpha-globulin stimulate differently the incorporation of exogenous DNA into L cells

J Keprtová, E Minárová, J Michl, V Spurná
  • PMID: 6183151

Isolated fractions of the growth-promoting alpha-globulin stimulate differently the incorporation of exogenous DNA into L cells

J Keprtová et al. Folia Biol (Praha). 1982.

Abstract

The growth-promoting alpha-globulin necessary for long-term cultivation of mammalian cells in serum-free medium is a complex of several proteins which also stimulates the incorporation of exogenous DNA into recipient L cells. Biological activity responsible for the stimulation of DNA incorporation into L cells can be concentrated because one of two major protein components, compared to the whole GPAG complex, increases incorporation into cell nuclei by 100%.

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