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Case Reports
. 1982 Nov;35(11):1253-67.
doi: 10.1136/jcp.35.11.1253.

Use of monoclonal antibodies for the histopathological diagnosis of human malignancy

K C Gatter, Z Abdulaziz, P Beverley, J R Corvalan, C Ford, E B Lane, M Mota, J R Nash, K Pulford, H Stein, J Taylor-Papadimitriou, C Woodhouse, D Y Mason
Case Reports

Use of monoclonal antibodies for the histopathological diagnosis of human malignancy

K C Gatter et al. J Clin Pathol. 1982 Nov.

Abstract

This paper describes the use of a panel of seven monoclonal antibodies (selected so as to include reagents reactive with both epithelial and lymphoid cells) for distinguishing between anaplastic carcinoma and high grade lymphoma. Details are given of the immunohistological reactions of these antibodies against a wide range of both normal and malignant tissues and of a number of practical instances in which use of the antibody panel enabled a diagnosis to be made when routine histological examination had been inconclusive.

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