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. 1982;14(12):1051-3.
doi: 10.1016/0020-711x(82)90160-4.

The crypto-OH radical in the damage of DNA by bleomycin-Fe2+?

A Bartkowiak, E Grzelinska, G Bartosz, J Zabłocka, W Leyko

The crypto-OH radical in the damage of DNA by bleomycin-Fe2+?

A Bartkowiak et al. Int J Biochem. 1982.

Abstract

1. Effects of various OH scavengers, superoxide dismutase and catalase on the formation of malondialdehyde-like products from DNA by bleomycin-Fe2+ were studied. In no case was a protective effect observed. 2. These results can be interpreted on the basis that a crypto-OH radical mediates the damage to DNA by bleomycin-Fe2+.

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