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. 1983 Feb 19;1(8321):378-81.
doi: 10.1016/s0140-6736(83)91499-x.

Transmission of cytomegalovirus among infants in hospital documented by restriction-endonuclease-digestion analyses

Transmission of cytomegalovirus among infants in hospital documented by restriction-endonuclease-digestion analyses

S A Spector. Lancet. .

Abstract

Over a 4-month period, 8 infants in an intensive-care unit were identified as excreting cytomegalovirus (CMV) in their urine. 7 of the 8 viral isolates were analysed by means of restriction-endonuclease-digestion analyses for molecular relatedness. CMV isolates from 3 babies had identical DNA-fragment migration patterns, indicating that all 3 babies were infected with the same strain of CMV. Epidemiological data indicate that CMV was transmitted from 1 infant to the other 2 babies through unidentified fomites within the nursery.

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