Transmission of cytomegalovirus among infants in hospital documented by restriction-endonuclease-digestion analyses
- PMID: 6185807
- DOI: 10.1016/s0140-6736(83)91499-x
Transmission of cytomegalovirus among infants in hospital documented by restriction-endonuclease-digestion analyses
Abstract
Over a 4-month period, 8 infants in an intensive-care unit were identified as excreting cytomegalovirus (CMV) in their urine. 7 of the 8 viral isolates were analysed by means of restriction-endonuclease-digestion analyses for molecular relatedness. CMV isolates from 3 babies had identical DNA-fragment migration patterns, indicating that all 3 babies were infected with the same strain of CMV. Epidemiological data indicate that CMV was transmitted from 1 infant to the other 2 babies through unidentified fomites within the nursery.
Similar articles
-
Molecular epidemiology of cytomegalovirus infections in premature twin infants and their mother.Pediatr Infect Dis. 1982 Nov-Dec;1(6):405-9. doi: 10.1097/00006454-198211000-00009. Pediatr Infect Dis. 1982. PMID: 6298754
-
Restriction endonuclease analysis of cytomegalovirus deoxyribonucleic acid as an epidemiologic tool.Pediatrics. 1982 Nov;70(5):717-21. Pediatrics. 1982. PMID: 6290975
-
Restriction enzyme analysis of cytomegalovirus DNA to study transmission of infection.J Clin Pathol. 1986 Mar;39(3):318-24. doi: 10.1136/jcp.39.3.318. J Clin Pathol. 1986. PMID: 3007581 Free PMC article.
-
Cytomegalovirus in human breast milk: risk to the premature infant.Breastfeed Med. 2006 Summer;1(2):99-107. doi: 10.1089/bfm.2006.1.99. Breastfeed Med. 2006. PMID: 17661570 Review.
-
Cytomegalovirus: epidemiology and infection control.Am J Infect Control. 1987 Jun;15(3):107-19. doi: 10.1016/0196-6553(87)90164-7. Am J Infect Control. 1987. PMID: 3039875 Review.
Cited by
-
In situ hybridization for the detection of cytomegalovirus (CMV) infection. Application of biotinylated CMV-DNA probes on paraffin-embedded specimens.Virchows Arch A Pathol Anat Histopathol. 1986;409(6):777-90. doi: 10.1007/BF00710763. Virchows Arch A Pathol Anat Histopathol. 1986. PMID: 3020777
-
Application of "Hirt supernatant" DNA to the molecular epidemiology of cytomegalovirus infections.J Clin Microbiol. 1984 Nov;20(5):1012-4. doi: 10.1128/jcm.20.5.1012-1014.1984. J Clin Microbiol. 1984. PMID: 6096394 Free PMC article.
-
Perinatal viral infections.Eur J Clin Microbiol. 1987 Jun;6(3):245-61. doi: 10.1007/BF02017608. Eur J Clin Microbiol. 1987. PMID: 3040392 Free PMC article. Review.
-
In situ hybridization for cytomegalovirus DNA in AIDS patients.Am J Pathol. 1988 Jun;131(3):490-6. Am J Pathol. 1988. PMID: 2837903 Free PMC article.
-
Comparative analysis of human cytomegalovirus a-sequence in multiple clinical isolates by using polymerase chain reaction and restriction fragment length polymorphism assays.J Clin Microbiol. 1990 Dec;28(12):2602-7. doi: 10.1128/jcm.28.12.2602-2607.1990. J Clin Microbiol. 1990. PMID: 1980680 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical