Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Dec;1(6):351-3.
doi: 10.1007/BF02019933.

Acridine orange staining of smears for demonstration of Mycobacterium tuberculosis

M L Katila, R A Mäntyjärvi

Acridine orange staining of smears for demonstration of Mycobacterium tuberculosis

M L Katila et al. Eur J Clin Microbiol. 1982 Dec.

Abstract

Acridine orange staining for the detection of mycobacteria was compared with staining by auramine O and with mycobacterial culture in a series of 1071 clinical specimens. A total of 78 (7%) specimens were positive by staining. No false positive or negative findings were recorded by the acridine orange method. The two fluorochromes proved equal in their ability to detect mycobacteria in specimens from culture positive cases of tuberculosis. In the rapid bacteriological diagnosis of tuberculosis, acridine orange offers a good alternative to auramine O which is considered carcinogenic.

PubMed Disclaimer

References

    1. IARC Monogr Eval Carcinog Risk Chem Hum Suppl. 1979 Sep;(1):1-71 - PubMed
    1. Z Erkr Atmungsorgane Folia Bronchol. 1970 Dec;133(1):462-4 - PubMed
    1. J Hyg Epidemiol Microbiol Immunol. 1979;23(3):307-17 - PubMed