Associated peptides isolated from human seminal fluid containing beta 2-microglobulin determinants

Abstract

Proteins in human semen that react with a monoclonal mouse antibody to human beta 2-microglobulin (h beta 2M) have been isolated using immunoaffinity chromatography. As well as material of the same size as h beta 2M, a peptide of approximately 18000 kdaltons was isolated. It is suggested that this substance either contains h beta 2-M sequences itself or, as is more likely, is non-covalently associated with an h beta 2M-like peptide chain.