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. 1978 Jan;76(1):175-83.
doi: 10.1083/jcb.76.1.175.

Lens differentiation. Crystallin synthesis in isolated epithelia from calf lenses

A J Vermorken, J M Hilderink, W J van de Ven, H Bloemendal

Lens differentiation. Crystallin synthesis in isolated epithelia from calf lenses

A J Vermorken et al. J Cell Biol. 1978 Jan.

Abstract

In the calf eye lens, four morphologically distinct cell types can be detected: three in the epithelial monolayer and one in the cortical part. During differentiation, there is a quantitative change in the synthesis of crystallin subunits. A marked increase in alphaA-chains and several beta-crystallin polypeptides accompanies the transition from epithelial to fiberlike lens cells while synthesis of the non-crystallin proteins diminishes significantly.

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