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. 1983 Jun 11;11(11):3559-69.
doi: 10.1093/nar/11.11.3559.

The sequence GGCmCGG is resistant to MspI cleavage

M Busslinger, E deBoer, S Wright, F G Grosveld, R A Flavell
Free PMC article

The sequence GGCmCGG is resistant to MspI cleavage

M Busslinger et al. Nucleic Acids Res. .
Free PMC article

Abstract

MspI essentially fails to cut the sequence GGCmCGG at enzyme concentrations which give total digestion of CCGG, CmCGG and GGCCGG sites. This result explains why certain sites in mammalian DNA are resistant to both MspI and HpaII and shows that this results from an idiosynchracy of MspI rather than a novel form of DNA methylation at this site in mammalian cells.

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References

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