Variations in the 5-hydroxy-indoleacetic acid concentration in the cerebrospinal fluid during the sleep-wake cycle in man
- PMID: 6190774
- DOI: 10.1007/BF02043435
Variations in the 5-hydroxy-indoleacetic acid concentration in the cerebrospinal fluid during the sleep-wake cycle in man
Abstract
A variation in the ventricular fluid 5-HIAA concentration has been observed during the phases of the sleep-wake cycle in man. This variation affects the NREM phase, during which 5-HIAA increases markedly, rather than the waking state and the REM phase. The results are discussed in relation to the possible relevance of serotonin to the sleep mechanism.
Similar articles
-
Extracellular levels of serotonin in the medial pontine reticular formation in relation to sleep-wake cycle in cats: a microdialysis study.Neurosci Res. 1993 Nov;18(2):157-70. doi: 10.1016/0168-0102(93)90018-l. Neurosci Res. 1993. PMID: 7510377
-
[Opposite variations of extracellular concentrations of 5-hydroxyindoleacetic acid (5-HIAA) measured by voltammetry of axonal terminals and cell bodies of the dorsal raphe nucleus through the sleep-wake cycle].C R Acad Sci III. 1988;307(18):817-23. C R Acad Sci III. 1988. PMID: 2464425 French.
-
Hypersomnia with simultaneous waking and sleep patterns in the electroencephalogram. A case report with neurotransmitter studies.J Neurol. 1979 Jul 11;221(1):1-13. doi: 10.1007/BF00313165. J Neurol. 1979. PMID: 92532
-
[Mathematical modeling of sleep-wake rhythms].Nihon Rinsho. 1998 Feb;56(2):499-503. Nihon Rinsho. 1998. PMID: 9503858 Review. Japanese.
-
Neural Circuitry of Wakefulness and Sleep.Neuron. 2017 Feb 22;93(4):747-765. doi: 10.1016/j.neuron.2017.01.014. Neuron. 2017. PMID: 28231463 Free PMC article. Review.