Interocular suppression in adults and infants using anaglyphic stimuli: visually evoked potential measures

Abstract

Interocular suppression, assessed by monocular VEP amplitude reduction, was investigated in 3 infants, average age of 3 months, and 8 adults. A dichoptic simultaneous masking paradigm was employed, the two eyes being disassociated by red and green filters which transmitted non-overlapping wave lengths of light (anaglyphic method). One eye was continuously presented with either darkness, a diffuse green light, or two green dot patterns, containing either 20' or 80' dots. The other eye was flashed with either red diffuse light, a red 20' dot pattern, or a red 80' dot pattern. In both adults and infants, monocular VEP amplitude was reduced as the size of the continuously presented dots increased (pattern suppression) and a smaller amplitude response occurred when dots of equal size were presented than when data of different size were presented (size-specific suppression). The relative and absolute magnitudes of interocular pattern suppression were similar for adults and infants. However, the relative and absolute magnitudes of size-specific suppression were larger for adults than for infants. Pattern interocular suppression was inferred to be relatively more mature in 3 month olds than size-specific suppression. The relative lack of size-specific suppression suggests a relative immaturity of binocular spatial frequency or size channels.