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. 1983 Jun;3(6):1157-62.
doi: 10.1128/mcb.3.6.1157-1162.1983.

Neural tissues express high levels of the cellular src gene product pp60c-src

P C Cotton, J S Brugge

Neural tissues express high levels of the cellular src gene product pp60c-src

P C Cotton et al. Mol Cell Biol. 1983 Jun.

Abstract

Chicken embryo tissues were examined for the expression of pp60c-src, the normal cellular homolog of the transforming protein of Rous sarcoma virus. Three assays, including a solid-phase radioimmunoassay, a competitive radioimmunoprecipitation assay, and an immune complex protein kinase assay, were employed. Elevated levels of pp60c-src were detected in lysates from several neural tissues, including brain, retina, and spinal ganglia. Other tissues contained 8- to 10-fold-lower levels of pp60c-src, levels comparable to those found in chicken embryo fibroblasts. Expression of pp60c-src in brain tissues was also shown to vary with the developmental stage of the embryo.

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References

    1. Proc Natl Acad Sci U S A. 1979 Jul;76(7):3116-20 - PubMed
    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. J Comp Neurol. 1981 May 10;198(2):293-306 - PubMed
    1. Proc Natl Acad Sci U S A. 1981 Jan;78(1):177-81 - PubMed
    1. Proc Natl Acad Sci U S A. 1978 Sep;75(9):4102-6 - PubMed

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