A precise termination site in the mouse beta major-globin transcription unit
- PMID: 6192441
- PMCID: PMC384110
- DOI: 10.1073/pnas.80.15.4694
A precise termination site in the mouse beta major-globin transcription unit
Retraction in
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A precise termination site in the mouse beta-major globin transcription unit.Proc Natl Acad Sci U S A. 1984 Apr;81(7):2274. doi: 10.1073/pnas.81.7.2274. Proc Natl Acad Sci U S A. 1984. PMID: 6371812 Free PMC article. No abstract available.
Abstract
Nascent labeled RNA from induced, globin-producing mouse erythroleukemia cells was hybridized to cloned regions of the beta major-globin gene. Transcription ceases about 1,000 bases downstream from the poly(A) site as indicated by protection from nuclease digestion of a discrete-sized RNA fragment that it shorter than the protecting cloned DNA fragment. This defines an apparently unique termination site for a protein-coding gene that is transcribed by RNA polymerase II.
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