[Effect of prolonged cold exposure on monoamine oxidase activity and kinetics and on serotonin metabolism in the rat brain]
[Article in
Russian]
- PMID: 6193823
Item in Clipboard
[Effect of prolonged cold exposure on monoamine oxidase activity and kinetics and on serotonin metabolism in the rat brain]
[Article in
Russian]
Biull Eksp Biol Med.
1983 Sep.
Abstract
Effects of long-term cold exposure on the content of serotonin and its metabolite 5-hydroxyindolacetic acid (5-HIAA) and monoamine oxidase (MAO) activity and kinetic parameters (Km and Vmax) of oxidative deamination of serotonin in rat brain stem. The increase of 5-HIAA level in the initial period of chronic cold exposure was determined by the blockade of active metabolite transport from the brain. The level of serotonin and the rate of its catalytic deamination by MAO were found to be decreased in cold-adapted rats. The magnitude of the Km of serotonin deamination was unchanged.
Similar articles
-
[Effect of short-term hypothermia on the monoamine oxidase system in the rat brain].Vopr Med Khim. 1982 Sep-Oct;28(5):36-40. Vopr Med Khim. 1982. PMID: 6184883 Russian.
-
[Monoamine oxidase in the rat brain in short-term exposure to high temperature].Vopr Med Khim. 1985 Jan-Feb;31(1):115-7. Vopr Med Khim. 1985. PMID: 3984267 Russian.
-
[Monoamine oxidase activity in the brain during adaptation to cold and simultaneous exposure to cold and hyperbaric oxygenation].Fiziol Zh SSSR Im I M Sechenova. 1981 Nov;67(11):1611-6. Fiziol Zh SSSR Im I M Sechenova. 1981. PMID: 7327272 Russian.
-
[Role of active transport of 5-hydroxyindoleacetic acid in serotonin metabolism in the brain].Ross Fiziol Zh Im I M Sechenova. 2004 Apr;90(4):490-4. Ross Fiziol Zh Im I M Sechenova. 2004. PMID: 15296070 Review. Russian. No abstract available.
-
[Dynamic changes of brain serotonergic and dopaminergic activities during development of anxious depression: experimental study].Usp Fiziol Nauk. 2004 Oct-Dec;35(4):19-40. Usp Fiziol Nauk. 2004. PMID: 15573884 Review. Russian.
Cited by
-
Neuromodulation and Synaptic Plasticity for the Control of Fast Periodic Movement: Energy Efficiency in Coupled Compliant Joints via PCA.Front Neurorobot. 2016 Mar 8;10:2. doi: 10.3389/fnbot.2016.00002. eCollection 2016. Front Neurorobot. 2016. PMID: 27014051 Free PMC article.
-
Metabolism and receptor binding of serotonin in brain structures during performance of a conditioned passive avoidance response.Neurosci Behav Physiol. 2005 Sep;35(7):685-92. doi: 10.1007/s11055-005-0111-4. Neurosci Behav Physiol. 2005. PMID: 16433063
-
Effects of active transport of 5-hydroxyindoleacetic acid on measures of serotonin metabolism in the brain.Neurosci Behav Physiol. 2005 Sep;35(7):769-71. doi: 10.1007/s11055-005-0122-1. Neurosci Behav Physiol. 2005. PMID: 16433074 No abstract available.