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. 1983 Jun;5(2):95-104.
doi: 10.1007/BF02796136.

On spatial periodicity in the formation of cell adhesions to a substrate

On spatial periodicity in the formation of cell adhesions to a substrate

L A Segel et al. Cell Biophys. 1983 Jun.

Abstract

Interference reflection microscopy reveals a fairly regular array of marginal focal contacts in early states of cell spreading. A theoretical explanation of the onset of patchiness is given, based on the positively cooperative binding to the substrate of laterally diffusing receptor molecules.

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