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. 1983 Dec;3(12):2298-301.
doi: 10.1128/mcb.3.12.2298-2301.1983.

Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene

L F Parada, R A Weinberg

Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene

L F Parada et al. Mol Cell Biol. 1983 Dec.

Abstract

Oncogenes have previously been reported in the DNAs of mouse fibroblast lines which had become transformed after in vitro exposure to the carcinogen 3-methylcholanthrene. These oncogenes are now shown to be versions of the cellular Kirsten ras gene and are therefore homologous to oncogenes detected in a variety of human tumor DNAs.

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References

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