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. 1978 Jan;113(1):87-9.
doi: 10.1001/archsurg.1978.01370130089017.

Effect of vagal stimulation on the concentration of gastrin in serum and antral mucosa in dogs

T Watayou, N I Ramus, J C Thompson

Effect of vagal stimulation on the concentration of gastrin in serum and antral mucosa in dogs

T Watayou et al. Arch Surg. 1978 Jan.

Abstract

The concentration of gastrin in serum and antral mucosa was studied in anesthetized dogs after electrical stimulation of the antral branch vagus nerve. Vagal stimulation caused immediate and sustained release of gastrin into the circulation. After stimulation for one hour, the gastrin concentration of antral mucosa increased significantly. This suggests that vagal release of gastrin triggers its rapid synthesis.

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