Characterization of antibodies to the structural polypeptides of HGSAg: evidence for subtype-specific determinants
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Characterization of antibodies to the structural polypeptides of HGSAg: evidence for subtype-specific determinants
J Immunol.
1976 Oct.
Abstract
Antisera prepared in guinea pigs to the structural polypeptides of HBAAg/adw and HBSAg/ayw were examined by a modified passive hemagglutination assay for antibodies to the subtype-specific d and y determinants. All of the isolated polypeptide fractions stimulated antibodies to both group specific and subtype-specific antigens of the native HBSAg particle from which they were derived. These data indicate that the polypeptides have similarities in their immunochemical structure.
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