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Comparative Study
. 1984 Apr 20;224(4646):289-2.
doi: 10.1126/science.6200929.

Characterization of exogenous type D retrovirus from a fibroma of a macaque with simian AIDS and fibromatosis

K Stromberg, R E Benveniste, L O Arthur, H Rabin, W E Giddens Jr, H D Ochs, W R Morton, C C Tsai
Comparative Study

Characterization of exogenous type D retrovirus from a fibroma of a macaque with simian AIDS and fibromatosis

K Stromberg et al. Science. .

Abstract

A novel type D retrovirus was isolated by cocultivation of explants of fibromatous tissue from a rhesus monkey (Macaca mulatta) with immunodeficiency and retroperitoneal fibromatosis. This type D virus, isolated from a macaque with simian acquired immunodeficiency syndrome (SAIDS-D/Washington), is exogenous and is partially related to the Mason-Pfizer and the langur monkey type D viruses. The SAiDS-D virus can be distinguished from all other primate retroviruses by antigenicity and molecular hybridization. Nucleic acid hybridization studies reveal that the origin of the SAIDS-D isolate may reside in Old World monkey (subfamily Colobinae) cellular DNA.

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