doi: 10.4269/ajtmh.1984.33.420.
A monoclonal antibody to surface antigens on microfilariae of Brugia malayi reduces microfilaremia in infected jirds
- PMID: 6203419
- DOI: 10.4269/ajtmh.1984.33.420
Item in Clipboard
A monoclonal antibody to surface antigens on microfilariae of Brugia malayi reduces microfilaremia in infected jirds
Am J Trop Med Hyg.
1984 May.
Abstract
A monoclonal antibody to surface antigens of Brugia malayi microfilariae promotes the adherence of peripheral blood cells to microfilariae in vitro and reduces microfilaremia in vivo. The antibody reacts with epitopes present on two stage-specific antigens with estimated molecular weights of 70,000 and 75,000 daltons.
Similar articles
-
Cross-reactive surface antigens on three stages of Brugia malayi, B. pahangi and B. timori.Parasitology. 1983 Oct;87 (Pt 2):249-63. doi: 10.1017/s0031182000052616. Parasitology. 1983. PMID: 6196709
-
Stage-specific and common antigens of Brugia malayi identified with monoclonal antibodies.J Immunol. 1984 Jun;132(6):3138-41. J Immunol. 1984. PMID: 6202774
-
Resistance against Brugia malayi microfilariae induced by a monoclonal antibody which promotes killing by macrophages and recognizes surface antigen(s).Immunology. 1985 Apr;54(4):655-63. Immunology. 1985. PMID: 3884492 Free PMC article.
-
Immunity in filariasis: perspectives for vaccine development.Annu Rev Microbiol. 1988;42:685-716. doi: 10.1146/annurev.mi.42.100188.003345. Annu Rev Microbiol. 1988. PMID: 3060005 Review. No abstract available.
-
Rodent models of filariasis.Contemp Top Immunobiol. 1984;12:275-321. doi: 10.1007/978-1-4684-4571-8_8. Contemp Top Immunobiol. 1984. PMID: 6365441 Review. No abstract available.
Cited by
-
Cloning and characterization of a potentially protective antigen in lymphatic filariasis.Proc Natl Acad Sci U S A. 1988 May;85(10):3604-7. doi: 10.1073/pnas.85.10.3604. Proc Natl Acad Sci U S A. 1988. PMID: 3368467 Free PMC article.
-
Protective immunity in bancroftian filariasis. Selective recognition of a 43-kD larval stage antigen by infection-free individuals in an endemic area.J Clin Invest. 1989 Jan;83(1):14-22. doi: 10.1172/JCI113850. J Clin Invest. 1989. PMID: 2642916 Free PMC article.
-
Molecular parasitology: progress towards the development of vaccines for malaria, filariasis, and schistosomiasis.Experientia. 1991 Feb 15;47(2):146-51. doi: 10.1007/BF01945415. Experientia. 1991. PMID: 2001716 Review.
-
Characterization of a monoclonal antibody against infective larvae of Brugia malayi.Immunology. 1988 May;64(1):169-74. Immunology. 1988. PMID: 3384450 Free PMC article.
-
Transmission-blocking antibodies recognize microfilarial chitinase in brugian lymphatic filariasis.Proc Natl Acad Sci U S A. 1992 Mar 1;89(5):1548-52. doi: 10.1073/pnas.89.5.1548. Proc Natl Acad Sci U S A. 1992. PMID: 1542646 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
