Naturally occurring anti-interferon antibodies in Lou/c rats
- PMID: 6203979
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Naturally occurring anti-interferon antibodies in Lou/c rats
J Immunol.
1984 Aug.
Abstract
Rats of the Lou/c strain have natural antibodies with binding and neutralizing activity against mouse and rat interferon. The antibodies can be purified on a column of goat IgG directed against rat IgG, and they have an affinity for protein A-Sepharose. They are already present in very young (2-wk-old) animals, and the titers increase with increasing age.
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